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In this article we discuss the correlation between complement system and COVID-19 infection and pharmacological solutions directed to regulate. The reduction of renal mass after radical nephrectomy (RN) for renal neoplasm, could be associated with compensatory hypertrophy of the contralateral kidney. The capacity of compensation will determine the renal function (RF) evolution. Measuring of total renal volume (TRV) of the remaining kidney pre and post RN can help assess the RF evolution. To determine the correlation between TRV pre and