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Besides, compared with the dysregulated modules detected by MCODE, CFinder and ClusterONE, the results of Netkmeans have higher accuracy, precision and F-measure. The experimental results show that the multiple dysregulated modules detected by Netkmeans are essential in the generation, development and progression of cancer, and thus they play a vital role in the precise diagnosis, treatment and development of new medications for cancer patients.Background Favorable cardiovascular health (CVH) in young adulthood has been associated with l