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63-37.59). This significantly increased the IRs for flares during the risk interval in both women (IR 27.65) and men (IR 15.3, all age groups (IR 17.00-37.84), with and without immunosuppressive agent (IR 24.29 and 28.45, respectively), and with and without prior respiratory diseases (IR 21.86 and 26.82, respectively). We found significant association between influenza infection and SLE flares resulting in hospitalization. Influenza infection has to be considered as a risk factor for flares in all SLE patients regardless of age, sex, med