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Extreme high blood pressure and AKI can be signs and symptoms of TMA in patients with SRNS. Strict anti-hypertensive treatment might improve renal results.Serious hypertension and AKI may be signs and symptoms of TMA in patients with SRNS. Strict anti-hypertensive therapy might improve renal effects. Splenic limited zone lymphoma (SMZL) is a rare lymphoid B-cell malignant neoplasm with primary involvement associated with spleen. It's a chronic condition