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ADHD Treatment Medication Many people with ADHD benefit from medication to improve their ability to focus and manage their behaviour. These drugs are known as stimulants. They work by changing how the normal brain chemicals, such as dopamine and norepinephrine, work. and guanfacine as well as other medications that are not stimulant-like assist with ADHD. Treatment can include psychotherapy, medication or a combination of both. Behavioral therapy is most effective when started when the diagnosis is