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The anatomy-mimetic design preserved normal knee kinematics in femoral rollback and internal rotation. The anatomy-mimetic design in lateral mobile UKA demonstrated restoration of normal knee kinematics. Such design may allow achievement of the long sought normal knee characteristics post-lateral mobile UKA. However, further in vivo and clinical studies are required to determine whether this design can truly achieve a more normal feeling of the knee and improved patient satisfaction.Cite this article 2020;9(7)421-428. The anatomy-mime