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Interestingly, discover a transition from the indirect semiconductor to a quasi-direct one for all PtX2 and Janus PtXY monolayers once the tensile strain is applied.A library of 57 substances of all-natural andrographolide had been designed, synthesized, and screened for in vitro scientific studies against four human disease mobile outlines A594, PC-3, MCF-7, and HCT-116. A lot of the synthesized compounds displayed better cytotoxic profile against all tested cells when compared to parent andrographolide (1). The