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Experiment 2 evaluated resurgence under conditions that better approximated those used in the clinic in which the alternative-response SΔ was present or absent. The SΔ failed to suppress target responding during resurgence testing in both experiments. These findings suggest that the conditions under which an alternative-response SΔ will successfully mitigate resurgence may be limited and require further research.Inherited retinal diseases (IRDs) are a diverse group of rare eye disorders, resulting in vision loss or blindness. The under