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037). Conversely, at individual level, after baseline trend correction, 7/10 patients improved on arm-hand-function Fugl-Meyer-Assessment (N = 4; p≤0.019), grip-strength (N = 3; p≤0.014), Motricity-Index (N = 4; p≤0.002), whereas 6/10 patients improved on arm-hand-skill-performance Action-Research-Arm-Test (N = 3; p≤0.042), ABILHAND (N = 5; p≤0.034). Application of botulinum-toxin-A may have an added-value in a substantial part of sub-acute stroke patients suffering from spasticity early post-stroke and who, at the point of therapy adm