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160, 95% CI = 0.037-0.698, P = 0.015), and time to Montreal Cognitive Assessment 3-point decrease (HR = 0.389, 95% CI = 0.160-0.946, P = 0.037), but had no relationship with time to tremor 4-point increase (HR = 1.638, 95% CI = 0.822-3.266, P = 0.161) and time to death (HR = 0.713, 95% CI = 0.219-2.319, P = 0.574). Our study indicated that ET history in patients with PD is associated with a benign prognosis with slower motor and non-motor progression.Glaucoma, a chronic neurodegenerative disease of retinal ganglion cells (RGCs), is a lea