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Individual stratification thinking about vertebral impairment is needed for further researches in this specific indication.Stereotactic biopsy (ST is commonly found in the pathological diagnosis of intracranial lesions. The associated complication and death prices tend to be reasonable, but few reports with big test sizes have actually assessed the problems of STB for lesions into the mind midline.To assess the problems of STB of lesions within the sellar region, pineal region, and brains