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The additional endpoint was hemorrhaging. Pooled effects were measured by relative risk (RR) with 95per cent confidence intervals (CIs). Publication prejudice ended up being examined with Egger's regression ensure that you modified by trim and fill method. RESULTS Twelve researches comprising 5829 CV patients with CYP2C19 loss-of-function alleles were included. Customers who received ticagrelor or prasugrel revealed a diminished threat of MACE compared to those just who