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Histologic analysis suggested myocardial injury in the REBOA group when compared with controls. This study demonstrates the feasibility of intermediate-term experiments in a complex swine model of polytrauma with 90minutes of REBOA. EVAC may be associated with improved survival at 24hours when compared with complete REBOA. EVAC resulted in normalized physiology after 24hours, suggesting that prolonged partial occlusion is possible. Longer studies evaluating partial REBOA strategies are needed. This study demonstrates the feasibility of