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The application of ultrasonication and heating enhanced the ability associated with the ionic liquid to draw out the analytes. Different variables that impact the removal performance had been investigated and enhanced utilizing single element experiments and response area design. The optimum circumstances associated with experiment were 121 µL of [HMIM][PF6] (extraction solvent), 794 µL of acetonitrile (dispersive solvent), a heating temperature of 40°C, a sonication perio