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In univariate Cox regression analysis, tumor depth, lymph node status, mean ADC, and kurtosis were significantly correlated with RFS (p = 0.047, p 3.24) showed a significantly worse RFS and DFS (p less then 0.001 and p = 0.006, respectively). CONCLUSIONS Histogram analysis of ADC may serve as a useful biomarker for ESCC, reflecting pathological features and prognosis.BACKGROUND The incidence of breast biopsy following treatment for breast cancer is not well-characterized. We sought to determine the frequency and outcomes of breast bi