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This paper reports on the trend of the stressogenic stimulus caused by a repeated exposure to 1-methylnaphthalene (1-MN) vapors at the nominal concentrations of 0 mg/m
<sup>3</sup> (the control restrainer), 50 mg/m
<sup>3</sup> or 200 mg/m
<sup>3</sup> in the nose-only inhalation system, by analyzing the serum corticosterone (CORT) levels in rats. Three groups of rats were exposed in restrainers to 1-MN vapors at the nominal concentrations of 0 mg/m
<sup>3</sup>, 50 mg/m
<sup>3</sup> or 200 mg/m
<sup>3</sup> for 5 days. One control g