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05). Of the 4 microRNAs, only miR-210-3p was upregulated in the rats with experimental varicocoele (P.01). In the patients with varicocoele, we found that seminal exosomal miR-210-3p significantly increased in patients with grade II and III varicocoele (P.01), and miR-210-3p negatively correlated with sperm count (P.01) and seminal inhibin-B expression (r=-0.39, P.01). For the 30 patients with microsurgical varicocelectomy, the operation notably decreased miR-210-3p (P.01). Seminal exosomal miR-210-3p may be a novel
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