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The significant postoperative survival benefit of statin users was seen despite a higher rate of cardiovascular comorbidity. Preoperative statin therapy displays a strong association with reduced postoperative mortality following surgical resection for rectal cancer. The results from the current study warrant further investigation to determine whether a causal relationship exists. Preoperative statin therapy displays a strong association with reduced postoperative mortality following surgical resection for rectal cancer. The results fro