https://www.selleckchem.com/pr....oducts/polyethylenim
Diabetes and Alzheimer's disease (AD) place a significant burden on health care systems in the world and its aging populations. These diseases have long been regarded as separate entities; however, advanced glycation end products (AGEs) and the receptors for AGEs (RAGE) may be a link between diabetes and AD. In our study, mice injected with AGEs through stereotaxic surgery showed significant AD-like features behavior showed decreased memory; immunofluorescence showed increased phosphorylated tau and APP. These results suggest l