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Further, KMT2D, an important mammalian histone H3K4 mono-methyltransferase, plays a vital role in regulating development, differentiation, k-calorie burning, and cyst suppression. Therefore, we proposed the theory that KMT2D CNV might have phenotypic effects on sheep development traits. In our research, KMT2D CNVs in three Chinese sheep types were detected by quantitative polymerase chain reaction (qPCR), as well as the loss copy had been found is the prominent genotype. Association analysis betw