https://www.selleckchem.com/pr....oducts/alw-ii-41-27.
To evaluate the efficacy of selective and non-selective inhibitors of cyclooxygenase-2 enzymes in the treatment of experimental apical periodontitis induced by bacterial lipopolysaccharide (LPS) in vivo in a mouse model. Thirty-six C57BL / 6 mice were used. After access cavity preparation, a solution containing E. coli LPS (1.0µg / µL) was inoculated into the root canals of the mandibular and maxillary right first molars (n=72) After 30 days, apical periodontitis was established and the animals were systemically treated with Celeco
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