https://www.selleckchem.com/products/im156.html
It is vital to remove residual tumor cells after resection to avoid the recurrence and metastasis of osteosarcoma. In this study, a mineral nanomedicine, europium-doped calcium fluoride (CaF2Eu) nanoparticles (NPs), is developed to enhance the efficacy of adjuvant radiotherapy (i.e., surgical resection followed by radiotherapy) for tumor cell growth and metastasis of osteosarcoma. In vitro studies show that CaF2Eu NPs (200 μg/mL) exert osteosarcoma cell (143-selective toxicity and migration-inhibiting effects at a Eu dopant amount of 2.