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Conclusions Our hypothesized typologies need validation in a prospective observational trial. If validated, they may allow for better clinician communication. Copyright (c) 2019 The Authors. Published by Wolters Kluwer Health, Inc. on behalf of the Society of Critical Care Medicine.1) To show how to exploit the information contained in the trajectories of time-varying patient clinical data for dynamic predictions of mortality in the ICU; and 2) to demonstrate the additional predictive value that can be achieved by incorporating this tr