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Results After treatments, DF group showed higher microhardness values than all the groups. Also, DEL20D group showed similar results with H group according to the microhardness analysis (p less then 0.05). Conclusions It could be concluded that Duraphat 5% treatment showed better results when compared with all tested groups, however, the association of ErYAG Laser 20 with Duraphat 5% also showed promising results.We report here an efficient and highly straightforward access to α-difluoromethylated ketones through a visible light-mediat