https://bucladesineactivator.c....om/bioanalytical-met
We unearthed that the mixed impact of Sirt3 and an HFD had been evident much more parameters in males (lipid content, sugar uptake, pparγ, cyp2e1, cyp4a14, Nrf2, MnSOD activity) compared to females (protein harm and mitochondrial respiration), pointing towards a higher dependence of males in the effect of Sirt3 against HFD-induced metabolic dysregulation. The male-specific outcomes of an HFD have reduced Sirt3 phrase in WT and eased lipid accumulation
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