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All told, it is evident that quantitatively derived, integrative models of personality-psychopathology represent a particularly promising conduit for advancing our understanding of the neurobiological foundation of human experience, both functional and dysfunctional.This essay examines the experience of conducting a "home-bound pandemic ethnography"-one that toggles back and forth between the ethnographer's own experience of the pandemic while in quarantine and the very different pandemic experiences of her Latina immigrant essential wo