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The aim of this study was to compare, through clinical and microbiological analysis, the use of multiple applications of aPDT as an adjuvant therapy to non-surgical periodontal treatment of stage III and IV grade C periodontitis in type 2 diabetic (DM2) patients. Thirty-four patients with non-compensated DM2 and periodontitis were randomly divided into two groups SRP Group (n=17) scaling and root planing (SRP); and SRP+aPDT Group (n=17) SRP followed by 3 consecutive aPDT applications, immediately, 48 and 96h after in pockets with probing
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