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In particular, SE reduced in the pain condition as compared to no-pain at specific frequency ranges. Hemodynamics, brain dynamics, and their interaction can discriminate situations of thermal pains perception. The possibility of monitoring on-line variations of thermal pains perception using such a class of measures is of high interest to study different pathologies affecting the peripheral nervous system, such as for instance, small fiber neuropathies, fibromyalgia syndrome, or painful diabetic neuropathy. The possibility of monitoring