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These findings contribute to understanding of the factors influencing problematic Internet use and how such factors interact. It also provides recommendations on how to prevent the progression of problematic Internet use and suggests possible interventions.Allogeneic hematopoietic stem cell transplantation (HSCT) and coronavirus disease 2019 (COVID-19) infection can both lead to severe cytokine release syndrome (sCRS) resulting in critical illness and death. In this single institution, preliminary comparative case-series study we compar