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0001), but in vehicle pretreated groups, RBF and RVR responses were different between male and female rats ( 0.05). AT R blockade increased RBF and decreased RVR responses to Ang II, and no difference between the sexes was detected. Coblockades of AT R and MasR receptors increased RBF response to Ang II significantly in males alone but not in females ( =0.04). The impact of Ang II on RBF and RVR responses seems to be gender related with a greater effect on males, and this sex difference abolishes by Mas receptor blockade. However,
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