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The evaluation of transmission electron microscopy, fourier change infrared spectroscopy and X-ray diffractometer unveiled that the quercetin ended up being effectively encapsulated in WPI-LRA, offering a top encapsulation effectiveness of 92.4 percent. Additionally, the WPI-LRA could substantially improve the storage stability and photochemical security of quercetin. The in vitro and in vivo experiments revealed that LRA-coated WPI hydrogel can allow quercetin become