https://www.selleckchem.com/pr....oducts/z-lehd-fmk-s7
Traumatic brain injury (TBI) is common in civilians and military personnel. No potential therapeutics have been evaluated to prevent secondary injury induced by the hypobaric hypoxia (HH) environment integral to post-injury aeromedical evacuation (AE). We examined the role of allopurinol, propranolol, adenosine/lidocaine/magnesium (ALM), or amitriptyline administration prior to simulated flight following murine TBI. Mice underwent TBI and were given allopurinol, propranolol, amitriptyline, or ALM prior to simulated AE or normob
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