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Recombinant DEL-1 augmented AMP-activated necessary protein kinase (AMPK) phosphorylation and haem oxygenase (HO)-1 appearance to alleviating swelling and impairment of insulin signalling in 3T3-L1 adipocytes treated with palmitate. siRNA of AMPK or HO-1 also mitigated the aftereffects of DEL-1 on inflammation and insulin resistance. DEL-1 ameliorates irritation and insulin weight in classified 3T3-L1 cells via AMPK/HO-1 signalling, suggesting that DEL-1 may be the exercise-mediated heali
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