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9%), morality, religion, and belief (8.5%), and alternative medicine (5.4%). There were also 1,223 pro-vaccine comments, of which 15.2% were offensive, mocking, or non-substantive. Sentiment analysis showed that comments without any arguments as well as those containing statements about alternative medicine or misinformation were more positive and less angry than comments in other topic categories.Conclusions The large amount of content in the conspiracy theory and misinformation categories may indicate that authors of such comments may