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This is the first reported Chinese family with FCL based on mutation in TREX1.PURPOSE This study aimed to summarize earlier studies on the effects of RS consumption on the serum levels of inflammatory biomarkers. METHODS A comprehensive search was done in the electronic databases that published from 1988 up to May 2019. Two reviewers independently performed screening, data extraction, and risk-of-bias assessment. We used from the effect size, as estimated by the mean difference to perform the fixed method meta-analysis. RESULTS Overall, 13 studies with 14 e