https://www.selleckchem.com/pr....oducts/Gefitinib.htm
05), reducing Bcl-2 Associated X (Bax) (p less then 0.05) and cleaved caspase-3 (p less then 0.05) of APP/PS1 mice. Moreover, Fasudil treatment also ameliorated the phosphorylation of p38 (p less then 0.01), c-Jun N-terminal kinase (JNK) (p less then 0.001) and extracellular regulated protein kinases (ERK) (p less then 0.001), and accelerated the nuclear factor-erythroid 2 p45-related factor 2 (Nrf2) (p less then 0.01) expression and its antioxidative downstream molecules (p less then 0.05, p less then 0.05, and p less then 0.05, resp