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Further studies are needed to better understand the role and neurobiology of depression, anxiety, and apathy in MCI. Copyright © 2020 Ma.The hippocampus features structurally and functionally distinct anterior and posterior segments. Relatively few studies have examined how these change during aging or in response to pharmacological interventions. Alterations in hippocampal connectivity and changes in glucose regulation have each been associated with cognitive decline in aging. A distinct line of research suggests that administration of
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