https://www.selleckchem.com/pr....oducts/climbazole.ht
Hepatic stellate cells (HSCs) activation, a critical event in liver fibrosis, has been recently shown to be related to autophagy. Determine whether chloroquine (CQ) could affect (i) the activation of HSC in vivo and (ii) the hepatic damage in a mice acute liver injury model. The acute liver injury was induced in BALB/c mice by carbon tetrachloride (CCl group); 24h before and after CCl administration animals were treated by CQ (CCl +CQ group). As control, mice treated by olive oil were considered. After 48h from CCl /olive oil adminis
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