https://epacadostatinhibitor.c....om/simultaneous-dete
Here we present RNA timestamps, a way for inferring age of specific RNAs in RNA-seq data by exploiting RNA modifying. To present timestamps, we tag RNA with a reporter motif comprising numerous MS2 binding sites that recruit the adenosine deaminase ADAR2 fused to an MS2 capsid protein. ADAR2 binding to tagged RNA causes A-to-I edits to build up with time, permitting age of the RNA is inferred with hour-scale reliability. By combining findings of mu