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A well balanced and renewable launch of aspirin from the nanofiber coatings could endure around 60 days. Such electrospun PLGA@ASA nanofiber coatings could promote proliferation and osteogenic differentiation of bone mesenchymal stem cells (BMSCs) along with inhibit M1 polarization and RANKL-induced osteoclast differentiation of macrophages in vitro. These results suggested that this facile formula of the PLGA@ASA nanofiber coatings for lasting medicine release could poss