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Depression at 30 days was more likely in women, diabetics and patients on dialysis (p = 0.024, p less then 0.001, p = 0.008, respectively). Patients with baseline moderate to severe depression were more likely to have moderate to severe depression at 30 days (p less then 0.001). Baseline depression was the strongest predictor of depression at 30 days. An increment of one unit of PHQ-9 baseline score increases the risk of developing severe depression at 30 days by 31%. Conclusion Depression was prevalent in our post-ACS patients. The asso