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SIRT2, a member associated with the Class III HDAC family, participates in diverse mobile procedures and regulates a few pathological conditions. Although a couple of reports reveal that SIRT2 regulates the cellular cycle, the causes and effects of SIRT2-dependent cell proliferation remain unclear. Right here, we examined the results of SIRT2 suppression in human RPE1 cells using siRNA targeting SIRT2, and AK-1, a SIRT2-specific inhibitor. The shee