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The biologic studies show that the goal receptor when it comes to virus might be angiotensin-converting enzyme 2 (ACE2). This peptide is in charge of changing angiotensin II (Ang II), that will be a profoundly active peptide, into Ang 1-7 with very a balancing barbell function. It's emphasized that the direct target regarding the virus is ACE2 underlining the obvious difference with ACE. Nevertheless, we hypothesized that a back load build up effect on Ang II may usurp the ACE capability