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Novel versatile nanomaterials may facilitate strategies for simultaneous soil remediation and agricultural production, but a thorough and mechanistic assessment of efficacy and safety is needed. We have established a new soil remediation strategy using nanoscale zero-valent iron (nZVI) coupled with safe rice production in paddy soil contaminated with pentachlorophenol (PCP). In comparison with rice cultivation in contaminated soil with 100 mg PCP per kg soil but without nZVI, the addition of 100 mg nZVI per kg soil increased grain yield