https://www.selleckchem.com/pr....oducts/gw806742x.htm
In recent years the functions of astrocytes have shifted from conventional supportive roles to also include active roles in altering synapses and engulfment of cellular debris. Recent studies have implicated astrocytes in both protective and pathogenic roles impacting Huntington's disease (HD) progression. The goal of this study is to determine if phagocytosis of cellular debris is compromised in HD striatal astrocytes. Primary adult astrocytes were derived from two HD mouse models; the fast-progressing R6/2 and slower progressing Q17
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