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The purpose of this comprehensive study was to evaluate the prospective protection of D-PLEX100 in abdominal surgical website. D-PLEX100 was administered into incisions of abdominal surgical website in Yucatan tiny swine, which were followed for up to 6 months and in comparison to sham-control swine. The D-PLEX100 mass would not move from the incisional site, and there was clearly no evidence for systemic toxicity or other safety issues. Surgical incision sites, such as the