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ism at position -308 (TNF -308). This involves substituting G allele for the A allele. We detected whether serum asprosin levels play a role in the occurrence and development of albuminuria in patients with type 2 diabetes mellitus (T2DM), which has not been previously discussed. Based on urinary albumin/creatinine ratio (UACR), 207 T2DM patients were divided into T2DM patients with normoalbuminuria (UACR30 mg/g), microalbuminuria (30≤UACR300 mg/g), and macroalbuminuria (UACR≥300 mg/g). Serum asprosin levels were determined by en