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The most common indication for LTOWB transfusion was hemorrhagic shock due to trauma. There were no clinically or statistically significant differences in baseline, post-transfusion day 1, or post-transfusion day 2 hemolysis markers between the group O and non-group O LTOWB recipients. There were no adverse events or transfusion reactions reported. Use of up to 40 ml/kg of LTOWB appears to be serologically safe for children in hemorrhagic shock. Use of up to 40 ml/kg of LTOWB appears to be serologically safe for children in hemorrhagic