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A head animation sub-system with graphical user interfaces was also developed. Model accuracy and system performances were analyzed. RESULTS The comparison with MRI-based model shows a very good accuracy level (distance deviation of ~1 mm in neutral position and an error range of [2-3 mm] for different facial mimic positions) for the generated model from our system. Moreover, the system speed can be optimized to reach a high framerate (up to 60 fps) during different head and facial mimic animations. CONCLUSIONS This study presents a nov