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Ergo, brand new strategies are required to develop far better and less toxic nanomedicines which could treat and manage the Leishmania parasite. One of these brilliant effective techniques is to construct nanometals with biologically active molecules that could have powerful antileishmanial activities with desirable biocompatibility. In this review paper, antileishmanial potencies of various steel nanoparticles, with specific increased exposure of biogenic steel nanoparticles from 2